Browsing PhD Dissertations - DO NOT EDIT by Title
Now showing items 21-40 of 173
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Characterization and Remediation of Wastewater from Unconventional Oil and Gas Development
(2018-08-24)Increasing energy demands from the nation and technological advancement in well development have led to the rapid expansion of unconventional oil and gas extraction. Current disposal methods for wastewater generated from ... -
Characterization Of Flavonoid Reactivities And Degradation Products Using Online Continuous Flow Kinetic Measurements And Higher Order Mass Spectrometry
(Chemistry & Biochemistry, 2014-03-12)Epidemiological studies offer strong evidence that diets rich in fruits and vegetables provide a defense against cardiovascular disease, cancer and other physiological disorders. One theory suggests that these hazards are ... -
COMBINING CHIRAL CHROMATOGRAPHIC STATIONARY PHASES AND N-DERIVATIZATION STRATEGIES FOR THE QUALITATIVE AND QUANTITATIVE ANALYSIS OF D-AMINO ACIDS, D-AMINO ACID CONTAINING PEPTIDES AND D-AMINO ACID RELATED SECONDARY METABOLITES USING LIQUID CHROMATOGRAPHY
(2023-05-12)Amino acids are essential building blocks in all life on Earth. It was first mistakenly believed that only L-amino acids were of biological relevance in higher organisms, and D-amino acids were laboratory artifacts or ... -
Computational materials chemistry: from polymer precursors to ceramics and high-pressure materials
(2022-08-17)With advances in computing power, the field of computational chemistry has flourished. Using current computational resources, atomistic simulations of billion atoms and trillions of atoms have been performed. Computational ... -
COPPER(I) AND SILVER(I) COMPLEXES OF OLEFINS, ALKYNES, AND CYCLOPROPENES AND THEIR APPLICATIONS
(2022-05-17)**Please note that the full text is embargoed until 5/9/2024** ABSTRACT: Poly(pyrazolyl)borates are very popular ligands in organometallic chemistry due to their attractive properties. It is easy to modify the steric and ... -
COPPER-BASED TERNARY OXIDE SEMICONDUCTORS FOR SOLAR ENERGY CONVERSION AND ENVIRONMENTAL REMEDIATION
(2019-09-04)Photoelectrochemical (PEC) water splitting using inorganic semiconductors is a promising approach to convert sunlight into sustainable fuels. However, many scientific and engineering challenges need to be overcome before ... -
Cytotoxicity Studies On Metallo-salens And Their Applications In Gene Delivery
(Chemistry & Biochemistry, 2009-09-16)Most of biological catalysts including nucleases are made of active metal centers. Metal complexes that are able to interact with DNA and RNA mimicking these natural nucleases will be valuable as therapeutic agents that ... -
DESIGN AND EVALUATION OF HMP KINASE ANALOGS AS THIAMINE PATHWAY INHIBITORS
(2016-08-15)Current bacterial chemotherapy faces an overwhelming reduction in efficacy due to an increase in bacterial resistance; resulting in a higher clinical demand for novel therapeutics and the investigation for their respective ... -
Design And Synthesis Of Flavin-based Organocatalysts For Biomimetic Aerobic Oxidation Reactions
(Chemistry & Biochemistry, 2014-03-12)Oxidation reactions are among the most costly and least selective transformations in synthetic chemistry. Catalytic methods that utilize O₂ as a terminal oxidant strive to reduce the inefficiency in this large area of ... -
Designing thermally stable ionic liquid stationary phases for gas chromatography and examining their structure-property relationships
(2018-11-30)Ionic liquids are popular in diverse scientific applications because of their unique physicochemical properties. The physicochemical properties of ionic liquids can be “tuned” by the modification of their structural moieties. ... -
DETERMINATION OF THE KINETIC ROLES OF THE MEMBRANE IN THE CATALYSIS OF RASGEFS BY USING AN ENGINEERED MODEL PROTEIN
(2021-08-10)Ras guanine nucleotide exchange factors (RasGEFs), which include Son of Sevenless (SOS), Ras Guanine Nucleotide Releasing Protein (RasGRP), and Ras Guanine Nucleotide Releasing Factor (RasGRF), catalyze nucleotide exchange ... -
Developing chemo-proteomics methods for tyrosine conjugation and studies of organometallic complexes of gold.
(2023-05-22)**Please note that the full text is embargoed until 05/14/2025** ABSTRACT: The incredible changes in MS instrumentation since the late 1980s with the advent of electrospray ionization (ESI) and matrix-assisted laser ... -
Development And Application Of New Mass Spectrometry-based Proteomics Technologies To Post-translational Modifications
(Chemistry & Biochemistry, 2009-09-16)Post-translational modifications (PTMs) represent one of the major cellular mechanisms to diversify the limited number of proteins coded by genome. They provide dynamic regulation of protein functions and the means to ... -
Development of Colorimetric and Fluorescent Antibiotic Biosensors and Synthesis of Drug-Related Biomimetic Molecules for Calcium Carbonate Polymorph Control and Stabilization
(2022-12-19)Polydiacetylene (PDA) polymers are conjugated macromolecules with desirable sensing properties. The presence of alternate double and triple bonds (en-yne subunits) generates electron delocalization in the PDA backbone, ... -
DEVELOPMENT OF HIGHLY POLAR STRUCTURALLY-TUNED IONIC LIQUIDS WITH UNIQUE SELECTIVITY FOR GAS CHROMATOGRAPHY
(2018-11-30)Ionic Liquids (ILs) are state-of-the-art fluids that have found broad application in separation science. Owing to their unique physicochemical properties such as low vapor pressure, high thermal stability, and high viscosity, ... -
DEVELOPMENT OF HPLC STATIONARY PHASES WITH UNIQUE SELECTIVITIES AND INTRODUCTION OF MOLECULAR ROTATIONAL RESONANCE SPECTROSCOPY IN GAS CHROMATOGRAPHY
(2020-11-23)This thesis contributes to advancing liquid and gas chromatography by introducing new stationary phases for HPLC and a new hyphenated GC technique. In the first section, new pH stable stationary phases based on geopolymers ... -
DEVELOPMENT OF INNOVATIVE THERANOSTIC PLATFORMS FOR BIOMEDICAL APPLICATIONS
(2019-08-12)Modern technologies have been successfully identifying patient’s disease-related genetic information and developing effective drugs continuously. The discovery of molecular biomarkers paves new roads for potential ... -
Development Of New Chiral Selectors For Liquid Chromatography And Their Performance Relative To Established Chiral Stationary Phases (CSPS)
(Chemistry & Biochemistry, 2010-03-03)HPLC with chiral stationary phases (CSPs) has proven to be the most widely applicable and versatile technique for enantiomeric separations. This dissertation discusses new research in three important areas of enantiomeric ... -
Development Of New Stationary Phases And Their Applications In High Performance Liquid Chromatography
(Chemistry & Biochemistry, 2013-10-22)High performance liquid chromatography (HPLC) has proven to be the most widely applicable and versatile technique in separation science. Hydrophilic interaction liquid chromatography (HILIC) has attracted considerable ... -
Development Of Paired Ion Electrospray Ionization Mass Spectrometry For Ultrasensitive Detection Of Anions
(Chemistry & Biochemistry, 2014-09-17)Mass spectrometry (MS) has emerged as an essential analytical technique over the last several decades. It is a widely applicable and powerful tool for determination and identification of different types of molecules. ...