Browsing PhD Dissertations - DO NOT EDIT by Issue Date
Now showing items 1-20 of 173
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Epigenetics Of HOXC13 Endocrine Regulation And Its Role In Gene Expression And Tumorigenesis
(Chemistry & Biochemistry, 12-10-2012)HOX genes are a subgroup of homeobox containing gene superfamily and have crucial roles in cell proliferation, cell differentiation, and embryonic development. HOXC13, one of 39 identified human HOX genes, is involved in ... -
Catalytic Hydro-liquefaction Of Lignite Coals Under Mild Conditions
(Chemistry & Biochemistry, 12-4-2012)A low-cost thermo-chemical process for the liquefaction of lignite coals is being developed at the University of Texas at Arlington (UTA). The coal-toliquids (CTL) project has focused of developing a liquefaction process ... -
Supramolecular Chemistry Of Nitrogen Dioxide
(Chemistry & Biochemistry, 2007-08-23)Supramolecular chemistry has been defined as "chemistry beyond molecules", and involves investigating molecular systems held together reversibly by inter-molecular forces, not by covalent bonds. This dissertation discusses ... -
Novel Functions And Physiological Significance Of Ral Interacting Protein - RLIP76 In In Vitro And In Vivo Models
(Chemistry & Biochemistry, 2007-08-23)This dissertation is divided into four parts. The first part is an introduction of energy dependent xenobiotic transporters and their relevance in multidrug resistance. However, the main focuse is the description of RLIP76 ... -
Investigation Of Ruthenium (II) Polypyridyl Dimers As Potential Chemotherapeutic Agents
(Chemistry & Biochemistry, 2007-08-23)The exploration of transition metal complexes as chemotherapeutic agents is still a relatively unexplored but promising area of research. Chapter 1 highlights the most successful anticancer drugs and potential drugs based ... -
Oligomeric And Polymeric Bibenzimidazole Based Metal Complexes And Crosslinked Polyethylenimine Based Flame Retardants
(Chemistry & Biochemistry, 2007-08-23)In Part I, a simple and mild condensation route for the synthesis of novel bibenzimidazole oligomers and polymers is described using methyl 2,2,2-trichloroacetimidate as a key starting material. The dimer, trimer, tetramer, ... -
Novel Approaches To Photoassisted Deposition Of Semiconductors And Nanocomposite Materials
(Chemistry & Biochemistry, 2007-08-23)This dissertation research begins with the use of TiO2-based photocatalysis for the reduction of metal ions with very negative reduction potentials. The indirect photocatalytic reduction of four metal ions: Cd2+, Zn2+, ... -
Studies Toward The Enantioselective Total Synthesis Of The Martinella Alkaloids
(Chemistry & Biochemistry, 2007-08-23)This dissertation consists of two parts. The first part describes the enantioselective total synthesis of martinellic acid. The Martinella alkaloids have attracted considerable attention in the synthetic community over the ... -
Calix[4]arene-based Synthetic Nanotubes
(Chemistry & Biochemistry, 2007-08-23)Nanoscale science and technology represents a tremendous opportunity to gain unprecedented insight into the unique phenomena that exists at the nanometer scale, and to use that knowledge to develop materials and devices ... -
Supramolecular Nanostructures Based On Calixarenes
(Chemistry & Biochemistry, 2007-08-23)This dissertation describes a systematic approach towards the design, synthesis, characterization, and application of calixarene-based supramolecular nanostructures. Chapter 1 briefly overviews the field of supramolecular ... -
New Applications Of The Pauson-Khand Reaction And Studies Towards The Synthesis Of The Hamigerans
(Chemistry & Biochemistry, 2007-09-17)This dissertation is divided into two parts. The first part describes the dicobalt octacarbonyl mediated synthesis of medium sized rings via intramolecular Pauson-Khand (IMPK) reaction. The cyclization of 1,8-enynes has ... -
Assemblies Of Assemblies: Supramolecular Ordering Of Nanoscopic Ruthenium Polypyridyl Building Blocks
(Chemistry & Biochemistry, 2008-04-22)Biological systems have long since perfected the development of nanoengineering. Cellular structure and machinery is based, to a significant extent, on the formation of nanometer to micron-sized assemblies of proteins. ... -
Ral Interacting Protein (Ralbp1): Linking Glutathione Conjugate Transport To Oxidative Stress Defenses And Signaling Pathways
(Chemistry & Biochemistry, 2008-08-08)The glutathione-conjugate transporter protein DNP-SG ATPase was demonstrated to be identical to the independently cloned Ral-effector, Ralbp1. Glutathione-conjugate transport is linked to substrate-stimulated ATPase activity, ... -
Ralbp1 In Stress Resistance
(Chemistry & Biochemistry, 2008-08-08)Ralbp1 is a multi-specific transporter of glutathione conjugates as well as unconjugated amphiphilic toxins. Because glutathione conjugates are major metabolites of toxic lipid peroxidation products generated as a consequence ... -
Synthetic Studies And Biological Evaluation Of Imidazole-containing Marine Alkaloids
(Chemistry & Biochemistry, 2008-08-08)This dissertation discusses the synthetic methods towards and the preliminary biological studies of an unnamed, imidazole-containing alkaloid, derived from the marine species Oceanapia. This alkaloid was first discovered ... -
Mass Spectrometry-based Biomolecular Recognition And Response Factor Investigations Using Electrospray Ionization
(Chemistry & Biochemistry, 2008-09-17)Integrins are transmembrane proteins found in almost all cells. They play vital roles in many biological processes, such as angiogenesis and signal transduction, through their interactions with different extracellular ... -
Plasma Surface Modifications For Biomedical And Electrical Applications
(Chemistry & Biochemistry, 2009-09-16)The focus of this work centers on molecular structuring of surfaces. The surface modifications were achieved using plasma polymerization technology, specifically variable duty cycle pulsed plasmas. The results obtained ... -
Mixed Lineage Leukemia Histone Methylases In Gene Expresion And Cancer
(Chemistry & Biochemistry, 2009-09-16)Histone methyl-transferases (HMTs) are key enzymes that post-translationally methylate nuclear histone proteins and play critical roles in gene expression, epigenetic regulation and diseases in eukaryotic organisms. Mixed ... -
Development And Application Of New Mass Spectrometry-based Proteomics Technologies To Post-translational Modifications
(Chemistry & Biochemistry, 2009-09-16)Post-translational modifications (PTMs) represent one of the major cellular mechanisms to diversify the limited number of proteins coded by genome. They provide dynamic regulation of protein functions and the means to ... -
Synthesis And Study Of Fluorinated Thiophenes, Bithiophenes And Trithiophenes: Models For The Polymeric Material
(Chemistry & Biochemistry, 2009-09-16)3-Fluorothiophene is a small molecule and the known syntheses for this molecule are far from being straight forward and suffer from many drawbacks such as low yield, long synthetic procedures and the use of expensive or ...