Browsing PhD Dissertations - DO NOT EDIT by Title
Now showing items 1-20 of 173
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ADVANCES IN LIQUID CHROMATOGRAPHY AND LIQUID CHROMATOGRAPHY MASS SPECTROMETRY FOR THE ANALYSIS OF BIOLOGICALLY IMPORTANT PHARMACEUTICALS, GLYCOSAMINOGLYCANS AND AMINO ACIDS
(2019-05-14)The use of high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) is now commonplace among pharmaceutical laboratories. They are major analytical tools in the drug discovery ... -
ADVANCES IN LIQUID CHROMATOGRAPHY AND LIQUID CHROMATOGRAPHY- MASS SPECTROMETRY FOR THE CHIRAL ANALYSIS OF AMINO ACIDS AND DIFFERENTIATION OF ISOMERIC AMINO ACID RESIDUES IN PEPTIDES/PROTEINS FROM COMPLEX MATRICES
(2019-11-20)Amino acids are essential building blocks in all living organisms. Initially it was believed that only L-amino acids were relevant in higher organisms, and D-amino acids were laboratory artifacts. Today, various D-amino ... -
ADVANCES IN SEPARATION AND DETECTION IN OPEN TUBULAR CHROMATOGRAPHY
Ion chromatography is an important method of analysis in the field of analytical chemistry with applications in a wide variety of applications from pharmaceutical analysis to purity assurance in semiconductor raw materials. ... -
Advances in Separation Methodologies: Fatty Acid, Fatty Amine, Water, and Ethanol Determination by Ionic Liquid Gas Chromatography and D-Amino Acid Evaluation in Mammalian Brain by Liquid Chromatography
(2016-08-15)This dissertation focuses on two chromatographic techniques, gas chromatography (GC) and high performance liquid chromatography (HPLC). The goal of the GC work is to describe advances in separation methodologies focusing ... -
ANALYSIS OF ISOTOPIC ISOMERS BY GAS CHROMATOGRAPHY AND MOLECULAR ROTATIONAL RESONANCE SPECTROSCOPY AND ENANTIOSELECTIVE METHOD DEVELOPMENT BY LIQUID CHROMATOGRAPHY
(2023-05-22)**Please note that the full text is embargoed until 05/14/2024** ABSTRACT: This dissertation focuses on developing improved methods and a better understanding of gas and liquid chromatographic separation of isotopic isomers ... -
ANALYTICAL METHODS FOR SOLVING COMPLEX PROBLEMS IN FOOD AND ENVIRONMENTAL SCIENCE
(2019-08-28)Complex samples can be challenging for analysis in a number of different ways. Food and environmental samples can be particularly difficult due to their non-uniformity from sample to sample, possible unknown contents, and ... -
Anion Detection In The Positive Ion Mode Electrospray Ionization Mass Spectrometry By Use Of Cationic Ion Pairing Agents: Behavior And Applications
(Chemistry & Biochemistry, 2013-07-22)Anion detection and quantitation has long been of great interest to many scientific areas of research in academic and industrial settings. Their importance extends to areas such as water and environmental analysis, biological ... -
APPLICATION OF NOVEL HETEROSUBSTITUTED VINYLIMIDAZOLES: AN APPROACH EN ROUTE TO THE TOTAL SYNTHESIS OF AXINELLAMINE A
(2016-05-11)Our group is primarily interested in the total synthesis of oroidin-based pyrrole-imidazole-containing marine sponge-derived alkaloids. These pyrrole-imidazole natural products are a growing class of alkaloids with exotic ... -
Application Of Pd-catalyzed Reactions In The Total Synthesis Of Oroidin-derived Alkaloids
(Chemistry & Biochemistry, 2014-03-17)The oroidin family of marine natural products is a growing group of sponge-derived alkaloids which contain 2-aminoimidazole and pyrrolecarboxamide fragments as their signature features. Due to their structural diversity ... -
Approaches Toward the Total Synthesis of Oroidin Alkaloids:Nagelamide A, C and Ageliferin
(2018-05-25)Nagelamides and ageliferin are oroidin-derived alkaloids which have gained the attention of the scientific community, because of their significant biological activity as well as the unprecedented structural diversity. Our ... -
AQUEOUS-BASED ASSOCIATED SOLVENTS FOR PROTEIN AND PEPTIDE FRACTIONATION AND PROTEIN PURIFICATION
(2022-01-03)The focus of this dissertation is studying capabilities of a novel two-phase system in enhancing protein identification in the whole-cell proteomics studies. In this document, two types of biphasic systems have been used ... -
Assemblies Of Assemblies: Supramolecular Ordering Of Nanoscopic Ruthenium Polypyridyl Building Blocks
(Chemistry & Biochemistry, 2008-04-22)Biological systems have long since perfected the development of nanoengineering. Cellular structure and machinery is based, to a significant extent, on the formation of nanometer to micron-sized assemblies of proteins. ... -
BAND GAP ENGINEERING IN TERNARY OXIDES AND SULFIDES: A ROUTE TO NEW PHOTOELECTRODES FOR SOLAR ENERGY CONVERSION
(2023-08-23)**Please note that the full text is embargoed until 08/01/2024** In recent years, there has been a growing interest in semiconductor photoelectrodes that can effectively split water into hydrogen and oxygen using sunlight. ... -
Bioanalytical LC-MS: Streamlined Sampled Preparation And Novel Ambient Ionization Techniques
(Chemistry & Biochemistry, 2012-07-25)Bioanalysis has gained importance in the scientific at an exponential rate. The focus of these works attempt to seek new approaches towards faster and more efficient bioanalysis that require little to no sample preparation. ... -
Biochemical, Kinetic And Spectroscopic Characterizations Of Non-heme Iron Oxygenase Enzymes
MiaE is a non-heme diiron enzyme which catalyzes the O2-dependent hydroxylation of selected tRNA-nucleotides as part of a multienzyme posttranscriptional hypermodification pathway. This tRNA-modifying enzyme is postulated ... -
Calix[4]arene-based Synthetic Nanotubes
(Chemistry & Biochemistry, 2007-08-23)Nanoscale science and technology represents a tremendous opportunity to gain unprecedented insight into the unique phenomena that exists at the nanometer scale, and to use that knowledge to develop materials and devices ... -
Capillary Scale Reagent Introduction And Optical Detectors For Capillary Scale Analysis
(Chemistry & Biochemistry, 2011-10-11)Atmospheric aerosols are of great interest as they have the potential to perturb the earth's radiative energy balance, influence the climate, reduce visibility, and adversely affect human health. The composition of atmospheric ... -
Catalytic C-C silylation Reactions
(2019-08-08)In my doctoral studies, the research is mainly focused on developing highly regio- and chemoselective C–C silylation of cyclopropanol derivatives with a hydrosilyl acetal directing group. This approach involves use of a ... -
Catalytic Hydro-liquefaction Of Lignite Coals Under Mild Conditions
(Chemistry & Biochemistry, 12-4-2012)A low-cost thermo-chemical process for the liquefaction of lignite coals is being developed at the University of Texas at Arlington (UTA). The coal-toliquids (CTL) project has focused of developing a liquefaction process ... -
CELL-FREE STUDIES OF CATALYTIC DNA CLEAVAGE BY RUTHENIUM POLYPYRIDYL COMPLEXES (RPCS) CONTAINING REDOX-ACTIVE INTERCALATING LIGANDS, ENANTIOMERIC SEPARATION AND SEMI-PREP SCALE PURIFICATION OF RPCS
(2018-08-28)Herein, we report the ruthenium (II) polypyridyl complexes (RPCs), [(phen)₂Ru(tatpp)] ²⁺ (3²⁺) and [(phen)₂Ru(tatpp)Ru(phen)₂] ⁴⁺ (4⁴⁺) are shown to cleave DNA in cell-free studies in the presence of a mild reducing agent, ...