Browsing Samir Iqbal, Ph.D. by Subject "Annealing"

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    • Electrical detection of single-base DNA mutation using functionalized nanoparticles 

      Iqbal, Samir M.; Christensen, Shawn; Goyal, Swati; Noor, Mohammud R. (Copyright American Physical Society,Department of Electrical Engineering, The University of Texas at Arlington, 2009-08-17)
      We report an electrical scheme to detect specific DNA. Engineered hairpin probe DNA are immobilized on a silicon chip between gold nanoelectrodes. Hybridization of target DNA to the hairpin melts the stem nucleotides. Gold ...