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DEVICES TO STUDY CANCER CELL BEHAVIOR
(2018-05-11)
Cancer is a major health concern that effects millions of people worldwide. The main contributing factor to the deadliness of the disease is cancer metastasis, where the cancer cells break away from the primary tumor site, ...
Electrical detection of single-base DNA mutation using functionalized nanoparticles
(Copyright American Physical Society,, 2009-08-17)
We report an electrical scheme to detect specific DNA. Engineered hairpin probe DNA are immobilized on a silicon chip between gold nanoelectrodes. Hybridization of target DNA to the hairpin melts the stem nucleotides. Gold ...
A mesoscale model of DNA interaction with functionalized nanopore
(Copyright American Physical Society,, 2009-11-30)
Functionalized nanopores have been used recently for the detection of specific DNA. The
interactions between the DNA and the nanopore are not well understood due to the small size of
DNA/nanopore and dynamic translocation ...