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New conductometric detection methods for sensitive ion chromatographic measurement of weak electrolytes
(2015-11-24)
Since Suppressed conductometric anion chromatography (SCAC) was proposed in the mid-1970s, SCAC has become a widely used tool for the determination of anion species in aqueous samples. Its application ranges from trace ...
SYNTHESIS OF MODIFIED RIBOSE SPIN-LABEL
(2015-11-24)
Transfer ribonucleic acids (tRNAs) from all organisms contain modified nucleosides, which are derived from four different nucleosides. Research has indicated that tRNA modifications affect translation and various metabolic ...
Thiol Dioxygenases: An Investigation Into The Mechanisms Of Cysteine Dioxygenase And 3-mercaptopropionic Acid Dioxygenase
(Chemistry & Biochemistry, 2015)
Thiol dioxygenase (TDO) enzymes catalyze the molecular oxygen-dependent oxidation of sulfur containing amino acid derivatives. The loss of the ability to regulate thiols has been linked to a number of neurological diseases. ...
EVALUATION OF ACTIVATED CARBON AS A COMMERCIAL DRUG DISPOSAL PRODUCT USING LIQUID CHROMATOGRAPHY–TANDEM MASS SPECTROMETRY
(2015-11-18)
At present, pharmaceuticals, synthetic organic compounds, and endocrine disrupting compounds are ubiquitous in our environment. These have been introduced by consumers and manufacturers directly and indirectly for decades. ...
Structure-Activity Relationships of Ruthenium(II) Polypyridyl Complexes with Redox-Active Intercalating Ligands: Correlation between Redox Activity, DNA Cleavage Capability and Cytotoxicity
(2015-12-10)
The investigation and development of transition metal complexes as cancer chemotherapeutics has gained a lot of interest in the past few decades and has become a promising area of research. Metal complexes of platinum and ...
DETERMINATION OF TOTAL AND D-AMINO ACID CONTENT IN MICE BRAIN TISSUE BY ACHIRAL-CHIRAL HEART-CUTTING TWO-DIMENSIONAL LIQUID CHROMATOGRAPHY: DIAGNOSTIC AND CLINICAL RELEVANCE AND A COMPARISON BETWEEN NON-PERFUSED AND PERFUSED TISSUE
(2015-11-24)
A heart-cutting two dimensional liquid chromatographic method for the quantification of free amino acid enantiomers from mouse brain tissue is demonstrated. Evidence to support the occurrence of D-amino acids in significant ...
NOVEL METHODS FOR IDENTIFICATION OF POSTTRANSLATIONAL LIPID MODIFIED PROTEINS BY MASS SPECTROMETRY
(2015-12-02)
Study of posttranslational modifications (PTMs) is very important for developing potential new drugs for the treatment of several diseases. Posttranslational lipid modifications are major PTMs which help proteins to anchor ...
Controlled Hydrosilylations of Carbonyl Compounds and Computational Investigations of a Hydride Shuttle Mechanism for Alkene Hydrosilylation
(2015-11-30)
Chapter 1 describes tandem dual hydrosilylations of α,β-unsaturated enals. Hydrosilylations of both carbonyl compounds and alkenes have been utilized to create chiral alcohols. Tandem dual hydrosilylations (TDH) of ...