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dc.contributor.authorKribs, Christopher
dc.contributor.authorJusot, Jean-Francois
dc.contributor.authorVanhems, Philippe
dc.contributor.authorCharles, Sandrine
dc.date.accessioned2016-05-26T16:02:28Z
dc.date.available2016-05-26T16:02:28Z
dc.date.issued2011
dc.identifier.citationPublished in the Bulletin of Mathematical Biology 73(7):1413-1442, July 2011en_US
dc.identifier.issn1522-9602
dc.identifier.urihttp://hdl.handle.net/10106/25676
dc.descriptionAuthor's final draft after peer review, also known as a post print.en_US
dc.description.abstractNosocomial transmission of viral and bacterial infections is a major problem worldwide, affecting millions of patients (and causing hundreds of thousands of deaths) per year. Rotavirus infections affect most children worldwide at least once before age five. We present here deterministic and stochastic models for the transmission of rotavirus in a pediatric hospital ward and draw on published data to compare the efficacy of several possible control measures in reducing the number of infections during a 90-day outbreak, including cohorting, changes in healthcare worker-patient ratio, improving compliance with preventive hygiene measures, and vaccination. Although recently approved vaccines have potential to curtail most nosocomial rotavirus trans- mission in the future, even short-term improvement in preventive hygiene compliance following contact with symptomatic patients may significantly limit transmission as well, and remains an important control measure, especially where resources are limited.en_US
dc.description.sponsorshipThis research was supported by a Marie Curie International Incoming Fellowship.en_US
dc.language.isoen_USen_US
dc.publisherSpringer-Verlagen_US
dc.subjectRotavirusen_US
dc.subjectNosocomial infectionsen_US
dc.subjectDynamical systemsen_US
dc.subjectStochastic modelen_US
dc.subjectPreventive measureen_US
dc.titleModeling nosocomial transmission of rotavirus in pediatric wardsen_US
dc.typeArticleen_US
dc.publisher.departmentDepartment of Mathematics and Curriculum & Instruction, University of Texas at Arlington
dc.identifier.externalLinkhttp://link.springer.com/article/10.1007/s11538-010-9570-z
dc.identifier.externalLinkDescriptionThe original publication is available at the journal homepage.


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