PhD Dissertations - DO NOT EDIT
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Partitioning the Role of Myocardial Steatosis on Left Ventricular Function
(2023-08-07)**Please note that the full text is embargoed until 8/1/2025** ABSTRACT: Preclinical studies have long suggested that excess lipid accumulation within cardiomyocytes (myocardial steatosis) leads to adverse cardiac remodeling ... -
Reducing Disparities in Physical Activity and Early Child Development: A Systematic and Observational Approach
(2022-08-15)**Please note that the full text is embargoed until 8/14/2024** ABSTRACT: Engaging in adequate (180 minutes per day) physical activity (PA) is an important component in positioning a young child towards optimal health. PA ... -
ELEVATED CARDIOVASCULAR DISEASE RISK IN BLACK FEMALES: THE IMPACT OF SOCIAL DETERMINANTS OF HEALTH AND NOVEL PREVENTIVE STRATEGIES
(2022-08-15)**Please note that the full text is embargoed until 8/14/2024** ABSTRACT: Among females in the United States, Black females suffer from the highest rates of hypertension, coronary artery disease, stroke, and total ... -
Investigating the Short-term and Long-term Impact of COVID-19 on Cardiovascular Health
(2022-08-15)Recent data indicates that the risk of developing cardiovascular disease (CVD) is augmented following coronavirus disease 2019 (COVID-19). Moreover, emerging data indicates that almost 50% of individuals who had COVID-19 ... -
AMORPHOUS SILICON OXYNITRIDE COATINGS FOR CRANIOFACIAL IMPLANTS STIMULATE OSTEOGENESIS VIA NRF2 ANTIOXIDANT ACTIVITY
(2022-12-13)Craniomaxillofacial injuries and defects are functionally and socially debilitating. These defects require immediate attention, and most cases undergo reconstruction surgery to restore the lost tissues. Current treatment ... -
SEX DIFFERENCES AND VASCULAR MECHANISMS OF ELEVATED CARDIOVASCULAR DISEASE RISK IN NON-HISPANIC BLACK INDIVIDUALS
(2021-08-05)Cardiovascular diseases (CVD), including hypertension, disproportionately affect the non-Hispanic black (BL) population in the United States. Despite being an inherently multifactorial process, altered vascular function ... -
Sympathetic Control of Blood Pressure in Young non-Hispanic Black Women
(2023-05-19)**Please note that the full text is embargoed until 05/15/2025** ABSTRACT: Non-Hispanic Black women in the United States have a greater prevalence of hypertension compared to non-Hispanic White women, which contributes to ... -
THE ROLE OF MUSCLE DAMAGE ON JOINT TISSUE
(2022-12-19)The musculoskeletal system is a highly diverse network of tissue that operates in conjunction to one other, both mechanically and biochemically. In states of disorder such as musculoskeletal disorders, this cross-communication ... -
Novel Mechanisms of Peripheral Vascular Dysfunction in Patients with Type 2 Diabetes
(2020-08-04)Currently, over 30 million adults in the United States have been diagnosed with Type 2 Diabetes mellitus (T2D). Importantly, T2D disproportionately augments the risk for the development of cardiovascular disease (CVD), ... -
Development and Clinical Application of a Novel Left Ventricular Diastolic Stress Test
(2020-05-14)Cardiology has long focused on the hearts ability to generate forward pressure and ejection of blood from the left ventricle to supply the systemic circulation with oxygen and nutrients. The ability and capacity of the ... -
INVESTIGATION INTO THE RELATIONSHIP BETWEEN POSTURE AND PSYCHOLOGY: THE PSYCHOLOGICAL RAMIFICATIONS OF FORWARD HEAD AND ROUNDED SHOULDER POSTURE
(2022-05-18)Embodied cognition speaks to the notion that the mind and body are inherently linked, and directly influence one another. Nonverbal communication experts hold the thought that sustaining chronic postures can impact an ... -
Dysregulated Calcium Signaling in Cardiomyocytes from Diabetic Atrial Fibrillation to Chemotherapy-Induced Cardiac Hypertrophy
(2020-08-13)Ca2+ is a vital second messenger in cardiomyocytes and controls excitation-contraction coupling. It also regulates cell cycle, apoptosis, hypertrophy and downstream gene transcription in the heart remodeling. Calcium ... -
BRAIN HEALTH AND ACTIVE LIVING: A SOCIAL ECOLOGICAL APPROACH
(2020-08-11)Advocating active lifestyles and improving brain health across the lifespan is one of the universal and ultimate goals for Healthy People 2030. Unhealthy movement behaviors (physically inactive, excessive sedentary behavior, ... -
Understanding Components of Motor Imagery Ability and the Association with Motor Proficiency in Children and Young Adults
(2020-07-13)Motor imagery (MI) refers to the imagination of a motor task without actual movement execution (Decety & Grézes, 2006) and is believed to represent one’s ability to accurately utilize forward internal models of motor control ... -
SHORT-TERM INTERMITTENT PARATHYROID HORMONE 1-34 ADMINISTRATION AND BONE VASCULAR ALTERATIONS IN C57BL/6 MICE
(2018-08-06)Advancing age is associated with progressive bone loss, declines in vasodilator capacity of blood vessels, vascular rarefaction and bone marrow blood vessel ossification. Intermittent parathyroid hormone (PTH) administration ... -
Trunk Function in Manual Wheelchair Users in Static and Dynamic Conditions
(2020-06-04)The relationship between functional capacity and trunk control is of significant interest to a variety of people, from wheelchair sport clinicians and professionals to rehab specialists, but has proven difficult to quantify. ... -
The Effects of Knee Joint Loading on Dynamic Tasks in Individuals Several Years Post-ACL Reconstruction
(2020-06-01)Joint loading of the lower extremity is studied to identify risk factors for anterior cruciate ligament (ACL) injuries and to determine limb asymmetries. Asymmetrical loading in the lower extremity during ACL reconstruction ... -
EXAMINING THE INFLUENCE OF SKELETAL MUSCLE OXYGEN METABOLISM ON MICROVASCULAR REPERFUSION IN RESPONSE TO ACUTE ISCHEMIA
(2019-12-03)Cardiovascular disease (CVD) is the single leading cause of morbidity and mortality in the United States (and the world), with a death rate greater than cancer and chronic lower respiratory disease (emphysema, bronchitis, ... -
Pathophysiology of Exercise Intolerance in Breast Cancer Survivors Treated with Anthracycline Chemotherapy
(2019-12-02)Anthracyclines emerged as frontline breast cancer adjuvant therapy in the late 1960’s. Within half a decade of their clinical adoption, dose-limiting cardiotoxicity was recognized and cumulative dose limits were established ... -
Whole Body Vibration as an Innovative Intervention to Improve Physical Function and Vascular Health within a Lifespan
(2019-09-06)Over the past several decades, technological advances in computers, transportation devices, and other automated devices have decreased the need for human locomotion and physical activity in the workplace and at home. The ...