Recent Submissions

  • Dual-Drug Containing Core-Shell Nanoparticles for Lung Cancer Therapy 

    Menon, Jyothi U.; Kuriakose, Aneetta; Iyer, Roshni; Hernandez, Elizabeth; Gandee, Leah; Zhang, Shanrong; Takahashi, Masaya; Zhang, Zhang; Saha, Debabrata; Nguyen, Kytai T. (NatureDepartment of Bioengineering, University of Texas at Arlington,, 16 October)
    Late-stage diagnosis of lung cancer occurs ~95% of the time due to late manifestation of its symptoms, necessitating rigorous treatment following diagnosis. Existing treatment methods are limited by lack of specificity, ...
  • A Dual-Modality System for Both Multi-Color Ultrasound-Switchable Fluorescence and Ultrasound Imaging 

    Kandukuri, Jayanth; Yu, Shuai; Cheng, Bingbing; Bandi, Venugopal; D’Souza, Francis; Nguyen, Kytai T.; Hong, Yi; Yuan, Baohong (MDPIDepartment of Bioengineering, The University of Texas at Arlington, 4 February)
    Simultaneous imaging of multiple targets (SIMT) in opaque biological tissues is an important goal for molecular imaging in the future. Multi-color fluorescence imaging in deep tissues is a promising technology to reach ...
  • The Mechanisms and Biomedical Applications of an NIR BODIPY-Based Switchable Fluorescent Probe 

    Cheng, Bingbing; Bandi, Venugopal; Yu, Shuai; D’Souza, Francis; Nguyen, Kytai T.; Hong, Yi; Tang, Liping; Yuan, Baohong (MDPIDepartment of Bioengineering, The University of Texas at Arlington, 11 Februar)
    Highly environment-sensitive fluorophores have been desired for many biomedical applications. Because of the noninvasive operation, high sensitivity, and high specificity to the microenvironment change, they can be used ...
  • Islet encapsulation - Strategies to enhance islet cell functions 

    Nguyen, Kytai T; Beck, ​Jonathan; Angus, Ryan; Madsen, Ben; Britt, David; Vernon, Brent (Mary Ann LiebertDepartment of Bioengineering, The University of Texas at Arlington, 2007)
    Diabetes is one of the most prevalent, costly, and debilitating diseases in the world. Although traditional insulin therapy has alleviated the short-term effects, long-term complications are ubiquitous and harmful. For ...
  • Effects of cyclic strain and growth factors on vascular smooth muscle cell responses 

    Nguyen, Kytai T; Kona, Soujanya; Xu, Hao; Chellamuthu, ​Prithiviraj; Hills, Seth R. (Bentham Open Access, 2009)
    Under physiological and pathological conditions, vascular smooth muscle cells (SMC) are exposed to different biochemical factors and biomechanical forces. Previous studies pertaining to SMC responses have not investigated ...
  • Targeted nanoparticles for cancer therapy: promises and challenge 

    Nguyen, Kytai T (OMICS Group InternationalDepartment of Bioengineering, The University of Texas at Arlington, 2011)
  • Enhanced endothelialization on surface modified poly(l-lactic acid) substrates 

    Nguyen, Kytai T; Xu, Hao; Timmons, Richard B; Deshmukh, Rajendrasing (Mary Ann LiebertDepartment of Bioengineering, The University of Texas at Arlington, 2011)
    Improved biodegradable vascular grafts and stents are in demand, particularly for pediatric patients. Poly (L-lactic acid) (PLLA) is an FDA-approved biodegradable polymer of potential use for such applications. However, ...
  • High-resolution imaging in a deep turbid medium based on an ultrasound-switchable fluorescence technique 

    Nguyen, Kytai T; Yuan, Baohang; Liu, Yuan; Alexandrakis, Georgios (American Institute of Physics (AIP)Department of Bioengineering, The University of Texas at Arlington, 2012)
    The spatial resolution of fluorescence imaging techniques in deep optically turbid media such as tissues is limited by photon diffusion. To break the diffusion limit and achieve high-resolution and deep-tissue fluorescence ...
  • Cytotoxicity evaluation of methacrylate-based resins for clinical endodontics in vitro 

    Wadajkar, Aniket S; Garza, Esteban G.; Ahn, Chul; Zhu, Qiang; Opperman, Lynn A.; Bellinger, Larry L.; Komabayashi, Takashi (Nihon University School of DentistryDepartment of Bioengineering, The University of Texas at Arlington, 2012)
    This study examines the cytotoxicity of Super-Bond C&B (SB-C&B), Super-Bond RC Sealer (SB-RC), MetaSEAL (Meta), and AH Plus Sealer (AH+). Freshly mixed and set materials (100 mg) were prepared in vitro and placed in ...
  • Biophysical assessment of single cell toxicity: diesel exhaust particle-treated human aortic endothelial cells 

    Nguyen, Kytai T; Xu, Hao; Wu, ​Yangzhe; Zhou, Anhong; Yu, Tian; Gilbertson, Timothy A. (PLOS (Public Library of Science)Department of Bioengineering, The University of Texas at Arlington, 2012)
    Exposure to diesel exhaust particles (DEPs), a major source of traffic-related air pollution, has become a serious health concern due to its adverse influences on human health including cardiovascular and respiratory ...
  • Multifunctionality of indocyanine green-loaded biodegradable nanoparticles for enhanced optical imaging and hyperthermia intervention of cancer 

    Nguyen, Kytai T; Patel, Ronak H; Patel, Nimet L; Kavuri, Venkaiah C; Liu, Hanli (SPIEDepartment of Bioengineering, The University of Texas at Arlington, 2012)
    The aim of this study was to develop and characterize multifunctional biodegradable and biocompatible poly lactic-co-glycolic acid (PLGA) nanoparticles loaded with indocyanine green (ICG) as an optical-imaging contrast agent ...
  • Mesenchymal stem cells as targeted cell vehicles to deliver drug-loaded nanoparticles for cancer therapy 

    Nguyen, Kytai T (OMICS Group InternationalDepartment of Bioengineering, The University of Texas at Arlington, 2013)
  • Nanomaterials for photo-based diagnostic and therapeutic applications 

    Nguyen, Kytai T; Menon, Jyothi U; Jadeja, Parth V; Tambe, Pranjali P; Vu, Khanh; Yuan, Baohang (IvyspringDepartment of Bioengineering, The University of Texas at Arlington, 2013)
    Photo-based diagnosis and treatment methods are gaining prominence due to increased spatial imaging resolution, minimally invasive modalities involved as well as localized treatment. Recently, nanoparticles (NPs) have ...