Browsing Department of Bioengineering by Title
Now showing items 171-190 of 338
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Kinetics Analyses Of Interactions Between Oncogenic And Tumor Suppressor Proteins By Quantitative High Resolution Microscopy Methods
(Biomedical Engineering, 2013-07-22)DAB2IP is correlated to the risk of aggressive prostate cancer and loss of DAB2IP not only leads to epithelial-to-mesenchymal transition (EMT), but also makes cells radioresistant. These observations support the notion ... -
Large Array EMG Monitoring Of Lumbar Region Muscle Action In Discogenic Low Back Pain
(Biomedical Engineering, 2007-08-23)This project explored the use of large array surface electromyography (LASE) as a technique for assessing the patterns of muscular activity under standardized loading conditions in patients with lumbar disc related pain ... -
LIGHT REFLECTANCE SPECTROSCOPY FOR THE DETECTION OF POSITIVE SURGICAL MARGIN OF PROSTATE CANCER
During a radical prostatectomy in the operating room, there exists a certain degree of risks of a surgical positive margin of prostate cancer. Positive surgical margins are defined as cancer that has spread beyond the ... -
Localization Of Biliary Tree Structures By Use Of Photon Diffusion Models
(Biomedical Engineering, 2008-08-08)A novel computational methodology is proposed for the intraoperative localization of biliary tree structures by means of spectrally resolved near-infrared reflectance measurements. As these structures are embedded in fatty ... -
Localized Treatment of Malignant Melanoma Using a Modified Cellulose-Based Hydrogel Loaded with Temozolomide with Increased Safety of Human Dermal Fibroblasts and the Mechanisms Behind the Effect
(2021-08-30)Melanoma pathophysiology is highly varied, and the initial cause of tumorigenesis is still unknown, but it is likely a combination of both epigenetic and genetic means. Further, melanoma tumors have one of the highest ... -
Long Gap Peripheral Nerve Reconstruction Using Decellularized Nerve Grafts
Peripheral nerve injuries that arise as a result of trauma, tumor excision or birth can adversely affect the quality of patient life, leading to lifelong disabilities in some cases. Autologous nerve grafts are the clinical ... -
LUNG CANCER TARGETED CHEMOTHERAPY VIA HERCEPTIN BASED CHIMERIC ANTIGEN RECEPTOR (CAR) ENGINEERED T CELL MEMBRANE COATED SYNTHETIC NANOPARTICLES
(2019-08-21)Cell membrane-derived nanoparticles recently caught attention due to their desirable features in drug delivery such as mimicking properties of native tissue and cells, avoiding systemic clearance, and alleviating foreign ... -
Lung protection by inhalation of exogenous solubilized extracellular matrix
(PLoS ONEDepartment of Bioengineering, The University of Texas at Arlington, 2017-02-02)Decellularized extracellular matrix (ECM) contains complex tissue-specific components that work in concert to promote tissue repair and constructive remodeling and has been used experimentally and clinically to accelerate ... -
Machine Learning and Deep Learning Applications in Neuroimaging
(2020-08-20)Deep Learning (DL) tools have the potential to analyze large datasets and extract meaningful insights to enhance patient outcomes. Radiological images such as MRI and CT, often contain complex patterns that can be difficult ... -
Magnetic Drug Targeting: Development Of A Novel Drug Delivery System For Prostate Cancer Therapy
(Biomedical Engineering, 2008-09-17)Magnetic nanoparticles (MNPs) have been attracting a great amount of attention because of their numerous applications including contrast agents in magnetic resonance imaging (MRI), magnetic targeted drug carriers, and ... -
MAGNETIC RESONANCE IMAGING OF CEREBROVASCULAR REACTIVITY USING GAS INHALATION CHALLENGES
(2016-01-06)Cerebrovascular reactivity (CVR) is a measure of dilation capacity of cerebral vasculature. It is an important biomarker for the vascular functionality and integrity, and may have clinical indications in stroke, ather ... -
Magnetic Resonance Spectroscopy Study Of Metabolic Profiles In Brain Tumors
(Biomedical Engineering, 2010-11-01)Metabolic profiles in brain tumors were measured using proton (1H) magnetic resonance spectroscopy (MRS) at 3T. Spectra were obtained from normal tissues and tumor mass regions of 6 low-grade gliomas, 7 anaplastic astrocytomas ... -
Magnetic-based Theranostic Nanoparticles For Prostate Cancer Management
(Biomedical Engineering, 2013-03-20)With an increasing rate of cancers, the need for effective cancer management has led to the development of theranostic systems for diagnosis and therapy. Conventional techniques for cancer management have limited success ... -
Magnetically Anchored "reduced Trocar" Laparoscopy: Evolution Of Surgical Robotics
(Biomedical Engineering, 2007-08-23)Laparoscopic surgery has become increasingly popular over the last few years due to its benefits; lower morbidity, less perceived pain, better cosmesis results, and less hospital time. For the surgeon however, there are ... -
Manipulating the K-Space for Reduction of Respiratory Induced Motion Artifacts
(2016-05-16)Respiratory induced motion artifacts, particularly those occurring in the abdomen and lung, pose a hefty problem in current diagnostic MR imaging. Application of images plagued with such artifacts not only hinder diagnosis, ... -
Mapping of Electroencephalogram (EEG) Responses to Newsvendor Decision Model and Cerebral Hemodynamic Responses to Transcranial Photobiomodulation (tPBM) in Humans
(2022-05-17)Decision-making is one of the most critical activities of human beings. Various studies have investigated the brain responses to a variety of decision tasks by deploying the EEG data. The first aim of my dissertation was ... -
MAPPING OF PREFRONTAL HEMODYNAMIC RESPONSES TO NOXIOUS STIMULATION AND CHRONIC PAIN RELATED RESTING-STATE FUNCTIONAL NETWORKS ASSESSED BY fNIRS
(2018-06-01)Neural representations of chronic pain are complex and are least understood. Numerous magnetic resonance imaging (MRI) studies have revealed structural and functional abnormalities in several cortical and sub-cortical ... -
MATHEMATICAL MODELING OF BLOOD PRESSURE AND CEREBRAL BLOOD FLOW USING PHOTOPLETHYSMOGRAPHY SIGNAL
(2019-05-22)Continuous and non-invasive monitoring of blood pressure (BP) and cerebral blood flow (CBF) has numerous clinical and health maintenance applications. Of particular interest is monitoring of BP and CBF during events that ... -
Measurement Of Cerebral Blood Flow Using Arterial Spin Labeling Method Across Lifespan
Arterial Spin Labeling (ASL) is one family of perfusion-weighted contrast imaging techniques of Magnetic Resonance Imaging (MRI) that measures cerebral blood flow by labeling spins in arterial blood with inversion and then ... -
Measurement Of Transverse Relaxation Times Of Cerebral Metabolites In Brain Tumors
(Biomedical Engineering, 2013-10-22)Proton (¹H) magnetic resonance spectroscopy (MRS) provides a non-invasive means of assessing metabolite concentration for a range of biologically important cerebral compounds in vivo. To extract quantitative information, ...